Sunday, January 15, 2012

Whole Genome Sequence for $1,000?

    According to an article in the Jan 10 issue of Wall Street Journal,  Life Technologies Corp is introducing a machine in the coming year which it claims can provide a whole genome sequence for any individual who wants one--for about $1,000.   And it can do it in a day.   A genome read out that quick and cheap could allow genetic sequencing to be used as a routine medical screening.  And as the price drops even further, such tests would be available to the entire population in most developed countries.
     The advantages would be: first, individuals could discover early in life whether they are particularly at risk for certain diseases, and take preventative action. Second, this information could guide therapists in tailoring treatments to the individual. And third, it could allow drug companies to develop specific drugs for different genetic types.  And forth, it would make it more practical for drug companies to develop drugs to mitigate the effects of certain genetic diseases, particularly those caused by a single mutation, by identifying the pool of individuals who might benefit from them.
     Of course, there could be a downside.   Once such information exists, it's only a matter of time before some of it falls into the hands of those who might use it to our disadvantage.  And eventually, such use might even be legal and institutionalized.  Have you seen the movie GATTACA?

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